Extreme hoarder Mary Thompson is in denial while Anne Thomas fears she's passing down her compulsion to son Brendan. For decades they've had trouble discarding their belongings but will they gain clarity and get the help they so desperately need?

In Brazil, a man lives with a disability that left his head upside-down.

Four-year-old twins hope doctors can perform a surgery to separate them.

A man develops a huge mass on his chin after suffering from bone cancer.

Bill's expectations are high as son William directs a funeral service.

Meet several couples that participate in the swinging lifestyle.

A conscious man is wheeled into the ER with a two-inch pipe through his head. A young bride is experiencing unstoppable bleeding and her groom is clueless. Two prisoners from rival gangs are suspiciously in the ER at the same time.

A new doctor must stand up to a superior who wants to send his wife into surgery with undiagnosed rectal bleeding. A man comes into the ER with a surprising body part stuck inside a camping stove. And a six-year-old boy has a rare massive stroke.

While a shooting victim is brought to the hospital, a Rottweiler gets loose in the ER. A young mother’s asthma attack turns quickly into a deadly heart failure. A young man comes into the ER comatose, covered with a mysterious rash.

A homemaker and energetic disc jockey experience bizarre occurrences.

A college student and a businesswoman experience bizarre occurrences.

A father and teenage girl experience bizarre occurrences.

A mom wakes up with a guardrail through her car.

A woman gives birth prematurely during Hurricane Sandy.

The trauma team treats a woman with a gunshot wound to her belly.

The trauma center sees victims of the bitter single-digit weather.