The staff at Charity Hospital treat a serious foot infection.

Dr. Donna Tesi deals with the extreme violence of the city.

Meet more of the staff as they treat a 15-year-old who was riding a three-wheeler through traffic & was struck by a truck, and a 9-year-old who was hit in the head by the metal A-Frame of a falling swing set. Both have life-threatening head injuries.

A 16 year old risks being expelled from school for behavioral issues.

A girls family decides to get involved in her campaign to be prom queen.

A woman gives birth prematurely during Hurricane Sandy.

Extreme hoarders Chris and Laurie are spiraling out of control. Their possessions are destroying their relationships and transforming their homes into virtual prisons. Change won't be easy, but it's their only hope of reclaiming their lives.

A 55-year-old man plans to abandon his hoard only to move back with his mother, a fellow hoarder. A woman's hoard is so severe that she runs the risk of having her house condemned.

Extreme hoarder Mary Thompson is in denial while Anne Thomas fears she's passing down her compulsion to son Brendan. For decades they've had trouble discarding their belongings but will they gain clarity and get the help they so desperately need?

A woman calls 911 after becoming locked inside her own car.

Experts respond to NYC's first biological attack since 2001: anthrax.

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A young boy is a frequent patient of the ER with persistent vomiting.

Doctors fear the worst until a radiologist makes a startling observation.

A man experiences recurring vomiting, heart palpitations and malaise.

Doctors suspect a woman is neurotic until her neighbors start getting sick.