Four-year-old twins hope doctors can perform a surgery to separate them.

A man develops a huge mass on his chin after suffering from bone cancer.

A baby is born with a tumor that takes the form of an extra head.

A girl born without arms and legs outshines her peers.

A mosquito bite inflates a man’s leg to five times its normal size.

A young girl undergoes a risky, life-saving operation on her face tumor.

The world’s tallest couple tries to control their children’s height.

A man is born with three legs and conjoined twins undergo risky surgery.

ER doctors in Sacramento, CA, deal with controlled chaos and tragedy.

An ER doctor must solve why a student is having difficulty breathing, and what his fraternity brothers might be hiding; a man falls off a roof and is impaled by a shovel; a police officer has a heart attack that endangers the hospital staff.

When 22 year-old Shelley Cushing collapses while skiing, doctors find nothing wrong with her, & suspect a 'complicated migraine'. Suddenly she is fighting for her life & doctors struggle to figure out what's happened to this seemingly healthy woman.

A teenager is rushed in with 6 gunshot wounds; a man's face is smashed in a motor vehicle accident; a professor comes in screaming in pain from a broken leg & fractured skull. Some of the staff finally get a chance to relax at a co-worker's wedding.