In emergency rooms across America, doctors, nurses and medical technicians work 24 hours a day to fight life-threatening injuries. Get an exhilarating look inside these ERs and witness the trials and tribulations of saving people's lives.

Embark on a voyage of discovery unlike any other and uncover the real stories of individuals living with the most mysterious and incredible medical anomalies, and celebrate the remarkable spirit of the individuals who have persevered.

Doctors recount the most memorable cases they’ve ever encountered. Unusual, touching, humorous or life-changing – no story is too big or too small when it comes to the ER. The patients’ lives are hanging in the balance and it’s up to the doctors to save them.

ER Files delves deep into the exciting world of the emergency department at Charity Hospital in New Orleans.

Investigate the science behind extraordinary, real-life medical stories and reveals the unseen mysteries of the human body hidden beneath the skin. This step-by-step, physiological narrative of patient rescues will immerse viewers in the stories that began as events unfold outside and the human body and progress inside; teetering on the brink of death to reveal these incredible stories.