In emergency rooms across America, doctors, nurses and medical technicians work 24 hours a day to fight life-threatening injuries. Get an exhilarating look inside these ERs and witness the trials and tribulations of saving people's lives.

Doctors recount the most memorable cases they’ve ever encountered. Unusual, touching, humorous or life-changing – no story is too big or too small when it comes to the ER. The patients’ lives are hanging in the balance and it’s up to the doctors to save them.

Embark on a voyage of discovery unlike any other and uncover the real stories of individuals living with the most mysterious and incredible medical anomalies, and celebrate the remarkable spirit of the individuals who have persevered.

Welcome to Vanderbilt, the toughest trauma center in America. As the only Level 1 trauma facility for 65,000 square miles, "Vandy" sees the worst injuries and the most critical patients with only one goal in mind, "Save every life, every time."

The patient is dying. The doctors are baffled. Nothing is what it seems. Clues and symptoms lead nowhere. The clock is ticking. Unless they find answers, people will die. These are real life stories, the most baffling medical mysteries straight from the Emergency Room. Weaving together interviews and re-enactments, Mystery E.R. follows doctors and investigators as they attempt to unravel the most unusual cases of their lives.

Matt & Amy Roloff enlist the help of their four children Jeremy, Zack, Molly & Jacob to help expand the business of Roloff farms. As the kids grow older, the family grows larger and the Roloffs learn how to keep their family relationships strong.

From construction to completion, Extreme Homes takes a personal tour of some of the most extraordinary homes in the world and reveals how each eccentric homeowner pushed the envelope as far as possible.

The stories of how and why items were invented and how their applications and manufacture have changed, often beyond recognition.

America: Fact vs Fiction is a wake-up call about the surprising hidden facts behind the most familiar and beloved stories from our nation's and military's past, filling in the blanks, debunking occasional myths, and exploring why we sometimes get our own history slightly wrong.

Comedian Noah Cappe seeks out freak show worthy foods at carnivals and fairgrounds across North America. He tries imaginative midway bites that have made food the new epicenter of carnival delights.

Thrill seekers take on the most over-the-top, adrenaline-filled and nail-biting water rides across the globe.

A six-member team of expert builders and designers travels the country to build luxurious, custom treehouses.