Doctors recount the most memorable cases they’ve ever encountered. Unusual, touching, humorous or life-changing – no story is too big or too small when it comes to the ER. The patients’ lives are hanging in the balance and it’s up to the doctors to save them.

Embark on a voyage of discovery unlike any other and uncover the real stories of individuals living with the most mysterious and incredible medical anomalies, and celebrate the remarkable spirit of the individuals who have persevered.

Accidents occur without warning, but what if it was your own doing that put yourself into a deadly situation? This series combines first-person accounts with dramatic recreations and real life footage to show that anyone can fall victim to a fatal self-inflicted injury.

In this compelling dramatic series, Sin City ER reveals the gritty real-life medical dramas that unfold behind Las Vegas’ glitzy façade at one of the most unique ERs in America: University Medical Center in Las Vegas.